Those with cataplexy tend to start experiencing symptoms between the ages of 7 and 25, but this disorder can strike at any time. However, it has been linked to a decrease of neurons that produce hypocretin - a neuropeptide hormone that manages your energy expenditure, awakeness, appetite, and arousal.Ī 2010 study found a loss of hypocretin is caused by an autoimmune response which leads to the production of trib 2 antibodies, which target and kill off hypocretin-producing neurons. The cause of cataplexy is a bit of a mystery to the medical world. This typically impacts both sides of the body but can be isolated to only one.Īlthough cataplexy is often associated with other diseases or sleep disorders, such as narcolepsy, stroke, excessive daytime sleepiness (EDS), multiple sclerosis, head injuries, and more, it can occur on its own. When cataplexy strikes, you lose control of your voluntary muscles for a period of time. What is Cataplexy and What Triggers It?Ĭataplexy is often triggered by sudden, intense emotions, including: We’ll break down everything you need to know about cataplexy, its symptoms, treatment methods, risks, and tips for living with it. However, cataplexy is not always linked to narcolepsy and can instead be caused by other genetic diseases or as a side effect of certain medications.Ĭataplexy is a complex, often misunderstood disorder that can greatly impact your daily life. There are two types of narcolepsy - those experiencing cataplexy are categorized as having narcolepsy type 1.
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